Biologics are produced from living organisms and range from proteins, like monoclonal antibodies, to peptide drugs up to vaccines as well as gene and cell therapy products. . They, are highly effective when compared to small molecule drugs due to their highly specific binding against one target. This results in less undesirable side-effects and low toxicity. By far, the commercially most successful biologics are monoclonal antibodies. They proved successful ,owing to their high epitope specificity and thereby negligible off-target effects. The advantages such as homogeneity, specificity, and large-scale production; and fewer side effects related to substitute drugs, have been the reasons for the steady market growth of new biologics in the past years.